Erscheinungsdatum: 04/2011, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: DEVELOPMENT OF GASTRO-RETENTIVE DRUG DELIVERY SYSTEM, Titelzusatz: A SCIENTIFIC APPROACH TO OVERCOME CHALLENGES IN GASTRO-RETENTIVE DRUG DELIVERY SYSTEM, Autor: KHARIA, ANKIT A. // K. SINGHAI, AKHLESH // SRIVASTAVA, M., Verlag: VDM Verlag, Sprache: Englisch, Rubrik: Medizin // Allgemeines, Lexika, Seiten: 152, Informationen: Paperback, Gewicht: 243 gr, Verkäufer: averdo
Erscheinungsdatum: 05/2012, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: A Novel Technique for Microencapsulation of Probiotic Bacteria, Titelzusatz: Development of a protection mechanism for guarding the healthy probiotic bacteria during their gastro-intestinal transit, Autor: Nag, Arup, Verlag: LAP Lambert Academic Publishing, Sprache: Englisch, Rubrik: Technik // Sonstiges, Seiten: 212, Informationen: Paperback, Gewicht: 327 gr, Verkäufer: averdo
A Novel Technique for Microencapsulation of Probiotic Bacteria ab 78.99 € als Taschenbuch: Development of a protection mechanism for guarding the healthy probiotic bacteria during their gastro-intestinal transit. Aus dem Bereich: Bücher, Wissenschaft, Technik,
DEVELOPMENT OF GASTRO-RETENTIVE DRUG DELIVERY SYSTEM ab 58.99 EURO A SCIENTIFIC APPROACH TO OVERCOME CHALLENGES IN GASTRO-RETENTIVE DRUG DELIVERY SYSTEM
Formulation & Development of Gastro-retentive Anti-Diabetic Tablet ab 49 EURO
Formulation & Development of Floating Drug Delivery System ab 49.9 EURO Formulation Development and Evaluation of Gastro Retentive Floating Drug Delivery System of Anti-platelet Drug
The purpose of writing this book on floating drug delivery systems (FDDS) was to compile the recent literature with special focus on the principal mechanism of floatation to achieve gastric retention. The existing techniques of gastro retention and popular concepts related to floating formulation are conferred in this book. The book mainly cover specific area including the physiological and formulation variables affecting gastric retention, practical approaches used for designing of single-unit (Tablets) and various essential formulation aspects. The book also summarizes the in vitro studies to evaluate the performance and application of floating systems. Several problems associated with the development of floating tablet dosage form are also address in this book
Inflammatory bowel disease is a common gastro-intestinal disorder marked with chronic inflammation of intestinal epithelium, damaging mucosal tissue and manifests into several intestinal and extra-intestinal symptoms. Currently used medical therapy aim to induce and maintain the patient in remission and ameliorate the disease's secondary effects, rather than modifying or reversing the underlying pathogenic mechanism. The main goal of this study is to evaluate the influence of erythropoietin, TDZD-8 and hemin, in a TNBS-induced colitis. Colitic mice are treated with daily doses of erythropoietin, TDZD-8 or hemin. TNBS-induced colitis was developed in 4 days, providing an acute intestinal inflammation model. These mice presented an increase of MPO, TNF- , IL-1beta and fecal hemoglobin. Erythropoietin treatment had a positive influence in the development of experimental colitis in all evaluated parameters, thus reducing its severity and extension. TDZD-8 nd hemin treatments had also a positive influence in the development of experimental colitis, but not in all evaluated parameters. All tested drugs significantly inhibit acute inflammatory response associated to the TNBS-induced colitis.
There are several reasons for the attractiveness of modified release dosage forms. For many disease states, a number of therapeutically effective compounds already exist. The goal in designing sustained or controlled delivery systems is to reduce the frequency of dosing and/or to increase the effectiveness of the drug by localization at the site of action, reducing the dose required or providing the uniform drug delivery. These systems have the obvious advantages of ease of administration and patient acceptance. Because of flexibility of dosage form design and their testing, oral sustained release systems have received a great deal of attention. The cost of formulation development, raw materials and manufacturing are significant factors in choosing formulation techniques and materials. The objective of this book is to discuss in a qualitative sense some of the advantages and challenges of Gastroretentive Drug Delivery Systems in comparison to controlled release formulations and to consider some contentious issues regarding the feasibility for Gastroretentive Drug Delivery systems for certain drugs. Attention will focus primarily on Oral Controlled RDDS.